isoThiocyanates. XXX. Glucohirsutin, a New Naturally Occurring Glucoside Furnishing (-)-8-Methylsulfinyloctyl isoThiocyanate on Enzymic Hydrolysis.
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چکیده
منابع مشابه
Naturally Occurring Isothiocyanates Exert Anticancer Effects by Inhibiting Deubiquitinating Enzymes.
The anticancer properties of cruciferous vegetables are well known and attributed to an abundance of isothiocyanates such as benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC). While many potential targets of isothiocyanates have been proposed, a full understanding of the mechanisms underlying their anticancer activity has remained elusive. Here we report that BITC and PEITC effe...
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Watercress is an exceptionally rich dietary source of beta-phenylethyl isothiocyanate (PEITC). This compound inhibits phase I enzymes, which are responsible for the activation of many carcinogens in animals, and induces phase II enzymes, which are associated with enhanced excretion of carcinogens. In this study, we show that watercress extracts are potent inducers of quinone reductase (QR) in m...
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Disruptions in whole-body lipid metabolism can lead to the onset of several pathologies such as nonalcoholic fatty liver disease (NAFLD) and cardiovascular diseases (CVDs). The present study aimed at elucidating the molecular mechanisms behind the lipid-lowering effects of the flavone luteolin-7-glucoside (L7G) which we previously showed to improve plasma lipid profile in rats. L7G is abundant ...
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The discovery of the first naturally occurring aromatic isothiocyanates, indole-3-isothiocyanates, their first synthesis, antimicrobial activity and proposed biogenetic origin in canola plants are reported.
متن کاملCell Cycle Arrest and Apoptosis in HT29 Human Colon Cancer Sulforaphane, a Naturally Occurring Isothiocyanate, Induces
Sulforaphane is an isothiocyanate that is present naturally in widely consumed vegetables and has a particularly high concentration in broccoli. This compound has been shown to block the formation of tumors initiated by chemicals in the rat. Although sulforaphane has been proposed to modulate the metabolism of carcinogens, its mechanism of action remains poorly understood. We have previously de...
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ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1958
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.12-0833